SYMPTOMS OF PANCREATIC CANCER

Sign and Symptoms of pancreatic cancer
Signs and symptoms of pancreatic cancer often don't occur until the disease is advanced. They may include:

Pain in the upper abdomen that radiates to your back
Loss of appetite or unintended weight loss
Depression
New-onset diabetes
Blood clots
Fatigue
Yellowing of your skin and the whites of your eyes (jaundice)

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STAGES OF PANCREATIC CANCER

There are mostly four STAGES of PANCREATIC cancer Stage I pancreatic cancer includes tumors which have not spread into certain proscribed sensitive areas and which have no involved regional nodes or distal metastasis. Stage II pancreatic cancer includes tumors which have spread into the duodenum, bile duct, or “peripancreatic” tissues AND which have no involved regional nodes or distal metastasis. Stage III pancreatic cancer includes tumors which may have OR may not have spread into these aforementioned areas and which have involved regional nodes, but which show no evidence of distal metastasis. Stage IVA pancreatic cancer includes tumors which have spread into the stomach, spleen, large bowel OR the adjacent large vessels AND which have involved regional nodes, but show no evidence of distal metastasis. And Stage IVB pancreatic cancer includes pancreatic tumors of any kind with node status of any kind AND with evidence of distal metastasis. For doctors and patients STAGES

FUNCTION OF PANCREAS

Your pancreas is about 6 inches (15 centimeters) long and looks something like a pear lying on its side. It releases (secretes) hormones, including insulin , to help your body process sugar in the foods you eat. And it produces digestive juices to help your body digest food. The pancreas is an organ located in the abdomen. It plays an essential role in converting the food we eat into fuel for the body's cells. The pancreas has two main functions: an exocrine function that helps in digestion and an endocrine function that regulates blood sugar. Exocrine Function: The pancreas contains exocrine glands that produce enzymes important to digestion. Most endocrine function of pancreas to produce specific enzymes. These enzymes include trypsin and chymotrypsin to digest proteins; amylase for the digestion of carbohydrates; and lipase to break down fats. When food enters the stomach, these pancreatic juices are released into a system of ducts that culminate in the main pancr

Clinical features of pancreatic cancer

Most patients have systemic appearance of the disease such as asthenia, anorexia, and weight loss. Other manifestations include deep and superficial venous thrombosis, panniculitis, features of obstructive jaundice, gastric outlet obstruction, increased abdominal girth, and depression. Obstruction of the pancreatic duct may lead to pancreatitis. Patients with pancreatic cancer often have dysglycemia. Indeed, pancreatic cancer should be considered in the differential diagnoses of acute pancreatitis and newly diagnosed diabetes. Physical examination may reveal jaundice, temporal wasting, peripheral lymphadenopathy, hepatomegaly, and ascites

Pancreatic cancer

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